The Personalized Psychological Treatment for Psychosis

NANot yet recruitingINTERVENTIONAL
Enrollment

252

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

May 31, 2026

Study Completion Date

May 31, 2026

Conditions
SchizophreniaPsychosisSchizophrenia Spectrum and Other Psychotic Disorders
Interventions
BEHAVIORAL

Psychological treatment (P-MCT)

Personalization will be performed according to the results obtained from the platform. Both the classic MCT and personalized MCT will be the same with regard to specific modules that are offered to patients. However, the personalized MCT will have personalized homeworks that target specific factors, in which patients have deficits. For instance, patients with deficits in self-esteem (based on the results from the platform) will be provided with homework addressing this aspect. We identified five domains that will be personalized: 1. self-esteem; 2. cognitive insight; 3. delusions; 4. positive symptoms; 5. completion.

BEHAVIORAL

Psychological treatment (MCT)

"Metacognitive training is a cognitive approach to the treatment of positive symptoms in psychosis.~Metacognitive training consists of ten modules referring to common cognitive issues and biases in solving problems in schizophrenia. The topics of MCT include the following: attribution blaming and taking credit (module 1), jumping to conclusions (modules 2 \& 7), changing beliefs (module 3), deficits in theory of mind and social cognition (modules 4 and 6), overconfidence in (memory) errors (module 5), mood (module 8), self-esteem (9) and stigma (10).~Each session lasts 45-60 min and follows a protocol defined in the 'Metacognitive Training for Psychosis (MCT)' manual.~The MCT for Schizophrenia programme will be applied to the group (6-12 persons) applied by therapists in each center. The training format (online or in-person) as well as the frequency (1 or 2 times per week) will vary depending on the center."

Trial Locations (6)

20246

University Medical Center Hamburg-Eppendorf, Hamburg

67091

University Hospitals of Strasbourg, Strasbourg

2340000

Universidad de Valparaíso, Valparaíso

00-378

The Institute of Psychology, The Polish Academy of Sciences, Warsaw

08950

Fundació Sant Joan de Déu, Barcelona

08034

Universitat Politècnica de Catalunya, Barcelona

All Listed Sponsors
collaborator

Fundació Sant Joan de Déu

OTHER

collaborator

Universitätsklinikum Hamburg-Eppendorf

OTHER

collaborator

University Hospitals of Strasbourg

UNKNOWN

collaborator

Universitat Politècnica de Catalunya

OTHER

collaborator

Universidad de Valparaiso

OTHER

lead

Polish Academy of Sciences

OTHER

NCT06603922 - The Personalized Psychological Treatment for Psychosis | Biotech Hunter | Biotech Hunter