Optimal Surgical Approach for Early-Stage Breast Cancer in Chinese Patients Aged ≤ 40 Years: a Cohort Study

CompletedOBSERVATIONAL
Enrollment

974

Participants

Timeline

Start Date

January 1, 2008

Primary Completion Date

December 31, 2019

Study Completion Date

January 1, 2024

Conditions
Breast Cancer
Interventions
PROCEDURE

MAST group

PROCEDURE

breast-conserving surgery plus adjuvant radiotherapy

Patients with early-stage (stage I, stage II, T≤2), and having the willingness to receive BCS were treated with BCS. All patients with BCS received post-surgery radiotherapy. Radiotherapy was administrated with a prescribed dose of 40 Gy in 15 fractions with photons and a boost of 10-16 Gy in 5-8 fractions with electrons to the ipsilateral breast. If axillary lymph nodes were involved, a conventional fraction was delivered with a prescribed dose of 50 Gy in 25 fractions to the ipsilateral breast and draining lymph node regions.

All Listed Sponsors
lead

West China Hospital

OTHER

NCT06603805 - Optimal Surgical Approach for Early-Stage Breast Cancer in Chinese Patients Aged ≤ 40 Years: a Cohort Study | Biotech Hunter | Biotech Hunter