Study on the Efficacy and Safety of Berberine, Minocycline, Esomeprazole, and Colloidal Bismuth Quadruple Therapy in the Initial Treatment of Helicobacter Pylori.

PHASE4RecruitingINTERVENTIONAL

Enrollment

548

Participants

Timeline

Start Date

November 20, 2023

Primary Completion Date

November 1, 2024

Study Completion Date

December 1, 2024

Conditions

Helicobacter Pylori InfectionChronic Gastritis

Interventions

DRUG

esomeprazole

Esomeprazole 40mg, twice daily for 14 days.

DRUG

Bismuth

Bismuth 220mg, twice daily for 14 days.

DRUG

Amoxicillin

Amoxicillin 1000mg, twice daily for 14 days.

DRUG

clarithromycin

clarithromycin 500mg, twice daily for 14 days.

DRUG

Berberine

Berberine 500 mg, twice daily for 14 days

DRUG

Minocycline

Minocycline 100 mg, twice daily for 14 days

Trial Locations (1)

RECRUITING

Xijing Hosipital of Digestive Disease, Xi'an

All Listed Sponsors

lead

Xijing Hospital of Digestive Diseases

OTHER