NCT06603662View on ClinicalTrials.gov

Systemic Oral Glucocorticoids for the Treatment of Acute Osteoarthritis Pain in the Emergency Department

PHASE4RecruitingINTERVENTIONAL
Enrollment

192

Participants

Timeline

Start Date

February 24, 2025

Primary Completion Date

October 31, 2027

Study Completion Date

December 31, 2027

Conditions
OsteoarthritisOsteoarthritis (OA) of the KneeOsteoarthritis (OA) of the ShoulderOsteoarthritis (OA) of the Hip
Interventions
DRUG

Prednisone

Subjects assigned to the Intervention A group will receive oral prednisone 50 mg once a day for 5 days, plus standard ibuprofen 600 mg every 8 hours for 5 days.

DRUG

Dexamethasone

Subjects assigned to the Intervention B group will receive a single oral dose of dexamethasone 10 mg, plus standard ibuprofen 600 mg every 8 hours for 5 days.

DRUG

Placebo

Subjects assigned to the Control group will receive oral placebo once a day for 5 days, plus standard ibuprofen 600 mg every 8 hours.

Trial Locations (1)

17403

RECRUITING

WellSpan York Hospital, York

All Listed Sponsors
lead

WellSpan Health

OTHER