110
Participants
Start Date
September 30, 2024
Primary Completion Date
October 31, 2025
Study Completion Date
December 31, 2025
preemptive stepwise infiltration anaesthesia(PSIA)
For PSIA patients, the anaesthetic is administered in stages. Initially, CA is injected at the incision site before the medial parapatellar incision. Following skin incision, more CA is injected into the subcutaneous tissue. After exposing the fascial layer and joint capsule, CA is used around the patellar tendon, and then CB is injected into the joint capsule and surrounding muscles. Additional CB is applied to the synovium and soft tissues after the joint cavity is opened, and more is used in the posterior joint capsule after bone resection.
postoperative local infiltration analgesia(PLIA)
Before standardized TKA and implantation of the prosthesis, 30-40 mL of CB will be used to infiltrate the synovium and whole joint capsule. Subsequently, the joint cavity, subcutaneous tissue, and skin will be closed layer by layer using routine procedures. After the skin is closed, 30-40 mL of CA will be injected into the skin and subcutaneous tissue.
RECRUITING
The First Affiliated Hospital of Fujian Medical University, Fuzhou
First Affiliated Hospital of Fujian Medical University
OTHER