Pathological Type,Gene Mutation and Clinical Characteristics of Unilateral Primary Aldosteronism

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

October 31, 2024

Study Completion Date

December 31, 2024

Conditions
Primary Aldosteronism
Interventions
OTHER

Tissue specimens were stained by histopathology of hematoxylin-eosin

Whole slide images were created by scanning the complete histologic slide to produce high-resolution digital files of the histopathology of hematoxylin-eosin and CYP11B2 immunostained sections.Tissue sections of all blocks from each resected adrenal were evaluated by hematoxylin and eosin and CYP11B2 immunostaining and adrenal specimens were categorized as classical or nonclassical histopathologic findings of unilateral PA according to the HISTALDO consensus; Genotyping was performed using CYP11B2 (aldosterone synthase)-guided sequencing

Trial Locations (1)

400016

RECRUITING

Qifu Li, PhD, Chongqing

All Listed Sponsors
lead

Qifu Li

OTHER