Proximal Gastrectomy Vs Total Gastrectomy in Locally Advanced Upper Gastric Cancer After Neoadjuvant Therapy

PHASE4RecruitingINTERVENTIONAL
Enrollment

404

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

December 30, 2026

Study Completion Date

December 30, 2028

Conditions
Locally Advanced Gastric Cancer
Interventions
PROCEDURE

Proximal radical gastrectomy

Proximal radical gastrectomy : Dissection of lymph nodes No.1,2,3a,4sa,4sb,7,8a, 9, 11p, 11dare recommended. The tumor involved more than 3cm of esophagus and additional dissection No.19, 20, 110. Gastrointestinal reconstruction method: double channel anastomosis is recommended, and other anastomosis methods can be carried out according to the surgeon\'s habit.

PROCEDURE

Total radical gastrectomy

total radical gastrectomy : Dissection of lymph nodes No.1-7, 8a, 9, 11p, 11d, 12a are recommended. The tumor involved more than 3cm of esophagus and additional dissection No.19, 20, 110. Gastrointestinal reconstruction method: Roux⁃en⁃Y anastomosis is recommended

Trial Locations (1)

430030

RECRUITING

Tongji Hospital, Huazhong University of Science and Technology, Wuhan

All Listed Sponsors
collaborator

Fudan University

OTHER

collaborator

Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine

OTHER

collaborator

The First Affiliated Hospital of Air Force Medicial University

OTHER

collaborator

Xiangya Hospital of Central South University

OTHER

collaborator

The First affiliated Hospital of Shandong Second Medical University

UNKNOWN

collaborator

Union Hospital, Tongji Medical College, Huazhong University of Science and Technology

OTHER

collaborator

The First Medical Center of Chinese PLA General Hospital

OTHER

collaborator

Affiliated Hospital of Qinghai University

OTHER

collaborator

Qilu Hospital of Shandong University

OTHER

collaborator

Ruijin Hospital

OTHER

collaborator

First Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Southern Medical University, China

OTHER

collaborator

Zhongnan Hospital

OTHER

collaborator

Shanxi Bethune Hospital

OTHER

collaborator

The First Affiliated Hospital of Zhengzhou University

OTHER

collaborator

Fujian Medical University Union Hospital

OTHER

collaborator

The Third Xiangya Hospital of Central South University

OTHER

collaborator

Jingzhou Central Hospital

OTHER

collaborator

Xiangyang Central Hospital

OTHER

collaborator

Yichang Central People's Hospital

OTHER

collaborator

People's Hospital of Macheng City

UNKNOWN

collaborator

The First Affiliated Hospital of University of South China

OTHER

lead

Guihua Wang

OTHER