NCT06594783View on ClinicalTrials.gov

Carvedilol Plus EVL or Not for the Primary Prevention of Esophageal Variceal Bleeding in Carvedilol Non-responders

PHASE4RecruitingINTERVENTIONAL
Enrollment

80

Participants

Timeline

Start Date

January 6, 2025

Primary Completion Date

October 31, 2030

Study Completion Date

October 31, 2030

Conditions
CirrhosisEsophageal Varices
Interventions
OTHER

Carvedilol plus endoscopic variceal ligation

Take carvedilol every day (start from 6.25 mg/d and then titrate to 12.5 mg/d if tolerable) and undergo EVL every 3-4 weeks until variceal eradication followed by regular endoscopic follow-up according to the protocol.

DRUG

Carvedilol alone

Take carvedilol alone every day (start from 6.25 mg/d and then titrate to 12.5 mg/d if tolerable).

Trial Locations (1)

11217

RECRUITING

Taipei Veterans General Hospital, Taipei

All Listed Sponsors
lead

Taipei Veterans General Hospital, Taiwan

OTHER_GOV