NCT06591494View on ClinicalTrials.gov

The Efficacy of Quadruple Therapy Containing Sodium Bicarbonate as the Primary Treatment for Helicobacter Pylori Infection

PHASE2/PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

855

Participants

Timeline

Start Date

September 15, 2024

Primary Completion Date

September 30, 2025

Study Completion Date

December 30, 2025

Conditions
Helicobacter Pylori Infection
Interventions
DRUG

Classic quadruple therapy

Esomeprazole 20 mg BID Bismuth pectin 200 mg BID Amoxicillin 1 g BID Clarithromycin 500 mg BID

DRUG

Quadruple therapy with sodium bicarbonate instead of bismuth

Esomeprazole 20 mg BID Sodium bicarbonate 500 mg TID Amoxicillin 1 g BID Clarithromycin 500 mg BID

DRUG

Quadruple therapy with sodium bicarbonate instead of clarithromycin

Esomeprazole 20 mg BID Bismuth pectin 200 mg BID Amoxicillin 1 g BID Sodium bicarbonate 500 mg TID

All Listed Sponsors
lead

Second Affiliated Hospital, School of Medicine, Zhejiang University

OTHER

NCT06591494 - The Efficacy of Quadruple Therapy Containing Sodium Bicarbonate as the Primary Treatment for Helicobacter Pylori Infection | Biotech Hunter | Biotech Hunter