Combining Aspirin With Ticagrelor or Clopidogrel in Large-vessel Minor Stroke or TIA

PHASE3RecruitingINTERVENTIONAL
Enrollment

900

Participants

Timeline

Start Date

September 1, 2024

Primary Completion Date

September 15, 2025

Study Completion Date

October 10, 2025

Conditions
Ischemic Stroke
Interventions
DRUG

Ticagrelor 90 MG

The ticagrelor arm will receive (a 180mg loading dose of cilostazol during the first 24 hours of stroke onset, followed by 90mg once daily from the 2nd day to the 90th day) and an open-label loading 300 mg aspirin, followed by a maintenance dose of 75 mg aspirin

DRUG

Clopidogrel

The clopidogrel arm will receive (a 300 mg loading dose of clopidogrel during the first 24 hours of stroke onset, followed by 75 mg once daily from the 2nd day to the 90th day) and open-label loading 300 mg aspirin, followed by a maintenance dose of 75 mg aspirin.

DRUG

Aspirin 75 Mg Oral Tablet

open-label loading 300 mg aspirin, followed by a maintenance dose of 75 mg aspirin for three months.

DRUG

Aspirin 75 Mg Oral Tablet

open-label loading 300 mg aspirin, followed by a maintenance dose of 75 mg aspirin for three months.

Trial Locations (1)

33511

RECRUITING

Kafr Elsheikh University Hospital, Kafr ash Shaykh

All Listed Sponsors
lead

Kafrelsheikh University

OTHER