Small Diameter TIPS in Patients with Severe Liver Atrophy and Variceal Bleeding

NANot yet recruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 15, 2024

Primary Completion Date

August 15, 2027

Study Completion Date

September 15, 2028

Conditions
Portal Hypertension Related to Cirrhosis
Interventions
DEVICE

During TIPS operation, shunt diameter or diameter of covered stent

"Transjugular intrahepatic portosystemic shunt (TIPS) is an effective treatment strategy for managing portal hypertension-related variceal bleeding. However, the appropriate diameter of the covered stent during the TIPS procedure remains a subject of debate. To date, there is a lack of strong evidence regarding the most suitable covered stent diameter.~Due to the lack of a dedicated 6-mm covered stent, we first released a 6-mm diameter stent (SD Express; Boston Scientific Co., or Luminexx; Bard Medical Division) in the liver parenchymal segment of the shunt, and then released an 8-mm TIPS stent (Viatorr; WL Gore \& Associates) to create a final 6-mm shunt."

DEVICE

During TIPS operation, shunt diameter or diameter of covered stent

After successful puncture, in the 8-mm shunt group, a balloon with a diameter of 6 mm was used to expand the shunt, and then an 8-mm covered stent was implanted (Viatorr; WL Gore \& Associates, Inc.).

All Listed Sponsors
lead

Huang Mingsheng

OTHER

NCT06589531 - Small Diameter TIPS in Patients with Severe Liver Atrophy and Variceal Bleeding | Biotech Hunter | Biotech Hunter