Lung Ultrasound Guided Fluid Balance Strategy in Patients with Lung Contusion

NANot yet recruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

October 31, 2025

Study Completion Date

October 31, 2025

Conditions
Lung Contusion
Interventions
OTHER

lung ultrasound guided fluid balance strategy

"Lung ultrasound (LUS) guided fluid management based on B-Line score assessment using LUS within 24 hours of icu admission and daily thereafter until icu discharge or for up to 14 days after randomization which ever comes first~In patients with BLS = 0-14, a zero fluid balance (FB) will be targeted if no signs of shock are present. In patients with BLS ≥ 15, a daily negative FB of -250 to -1000 mL will be targeted until BLS drops under 15. To reach daily targeted FB, furosemide-induced diuresis and RRT will be used In case of shocked patients with BLS \< 15: they will receive fluid boluses and packed RBCs to achieve a Hb of 10 and a MAP of \>65 mmHg.~In case of shocked patients with BLS ≥ 15: they will start norepinephrine infusion to reach a MAP of \>65 mmHg."

OTHER

usual care guided fluid balance strategy

fluid balance management will be guided to maintain an adequate intravascular volume while minimising weight gain within 24 hours of icu admission and daily thereafter until icu discharge or for up to 14 days after randomization which ever comes first. Various parameters will be used to attain this goal based on case-by-case clinical judgment: lung sounds, heart rate, blood pressure, temperature, urine output, lactate, haemoglobin, haematocrit, serum urea, creatinine, sodium, potassium, chloride, and bicarbonate values To reach daily targeted fluid balance, furosemide-induced diuresis and RRT will be used

Trial Locations (1)

71515

Faculty of Medicine, Assiut University, Asyut

All Listed Sponsors
lead

Assiut University

OTHER

NCT06586060 - Lung Ultrasound Guided Fluid Balance Strategy in Patients with Lung Contusion | Biotech Hunter | Biotech Hunter