Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15)

CompletedOBSERVATIONAL
Enrollment

503,325

Participants

Timeline

Start Date

January 31, 2006

Primary Completion Date

November 30, 2022

Study Completion Date

November 30, 2022

Conditions
Myocardial InfarctionIschemic StrokeAngina PectorisCoronary RevascularizationAll-cause MortalityCardiovascular DeathType 2 DiabetesHeart FailureAtrial FibrillationCancerDementiaDepressionInfectionsInjuriesLiver Cirrhosis
Interventions
BEHAVIORAL

Moderate drinking

Drink up to 16 grams of alcohol daily or almost daily \[repeated assessment center visit\] or 8-16 grams of alcohol 4 or more times per week \[web-based mental health questionnaire\]

BEHAVIORAL

Quitting

No alcohol consumption

BEHAVIORAL

Social drinking

Drink up to 16 grams of alcohol 1-2 days per week or drink 1-3 times per month or only on special occasions \[repeated assessment center visit\], or drink 8-16 grams of alcohol 2-3 times per week or drink 4 times per month or less \[web-based mental health questionnaire\]

BEHAVIORAL

Heavy/binge drinking

Drink more than 16 grams of alcohol daily or almost daily or more than 40 grams of alcohol 1-2 days per week \[repeated assessment center visit\], or 24 grams of alcohol or more 4 or more times per week or 40 grams of alcohol or more 2-3 times per week \[web-based mental health questionnaire\]

All Listed Sponsors
lead

Harvard School of Public Health (HSPH)

OTHER

NCT06583161 - Emulation of the Moderate Alcohol and Cardiovascular Health Trial (MACH15) | Biotech Hunter | Biotech Hunter