NCT06582940View on ClinicalTrials.gov

Elimination of PTV Margins Based on MRI-guided Adaptive Stereotactic Radiotherapy for Non-small Cell Lung Cancer With Brain Metastasis

PHASE2RecruitingINTERVENTIONAL
Enrollment

168

Participants

Timeline

Start Date

March 1, 2024

Primary Completion Date

March 1, 2026

Study Completion Date

March 1, 2026

Conditions
MRI-guided Adaptive RadiotherapyNon-small Cell Lung CancerBrain Metastasis
Interventions
RADIATION

MRI-guided adaptive SRT

MRI-guided online adaptive SRT (without PTV expansion margin). The total dose will be 30Gy/5 fractions, administered once daily. MRI will be acquired.

RADIATION

Conventional SRT

Conventional SRT (with PTV expansion margin). The total dose will be 30Gy/5 fractions, administered once daily. CBCT will be acquired.

Trial Locations (1)

510060

RECRUITING

Sun yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER