Defining Outcome Measures for Behavioural and Emotional Problems in Dystrophinopathies

RecruitingOBSERVATIONAL
Enrollment

100

Participants

Timeline

Start Date

September 13, 2022

Primary Completion Date

November 19, 2024

Study Completion Date

December 31, 2024

Conditions
DMDBMD
Interventions
BEHAVIORAL

Classical conditioning task

To evaluate the neurophysiological and physiological response to a classical conditioning task, which is comparable to findings that have been made in the mdx dystrophic mouse (deficient in Dp427). The investigators will assess correlations between the specific DMD/BMD genotype and susceptibility to conditioning, as well as the relationship between conditioning and behavioural/emotional characteristics of the syndrome.

Trial Locations (1)

WC1N 1EH

RECRUITING

UCL GOS Institute of Child Health, London

All Listed Sponsors
collaborator

Sarepta Therapeutics, Inc.

INDUSTRY

lead

University College, London

OTHER