Implantation of Engineered Cartilage Grafts for Treatment of Patellofemoral Osteoarthritis Versus Surgical Comparators.

PHASE2RecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

July 15, 2025

Primary Completion Date

January 31, 2029

Study Completion Date

January 31, 2030

Conditions
Patellofemoral Osteoarthritis
Interventions
BIOLOGICAL

Engineered cartilage graft (N-TEC)

Nasal chondrocytes based tissue engineered cartilage

PROCEDURE

Autologous Matrix Induced Chondrogenesis (AMIC)

Autologous Matrix Induced Chondrogenesis is performed through bone drilling and covering with Chondro-Gide® to attract bone marrow stem cells

PROCEDURE

Patellofemoral Arthroplasty (PFA)

Surgical implantation of a medical device, Zimmer Gender Solutions Patellofemoral Joint Prosthesis.

Trial Locations (11)

80

NOT_YET_RECRUITING

Department of Orthopaedics, University of Gothenburg (UGOT), Mölndal

1130

NOT_YET_RECRUITING

Orthopedic Hospital Vienna-Speising, Vienna

4031

NOT_YET_RECRUITING

University Hospital Basel, Basel

4054

RECRUITING

Crossklinik, Basel

10000

NOT_YET_RECRUITING

University Hospital Sveti Duh, Zagreb

13589

NOT_YET_RECRUITING

Evangelisches Waldkrankenhaus Spandau, Berlin

20157

NOT_YET_RECRUITING

IRCCS Ospedale Galeazzi-Sant'Ambrogio, Milan

97074

NOT_YET_RECRUITING

Orthopedic Clinic König-Ludwig-Haus, Würzburg

00128

NOT_YET_RECRUITING

Fondazione Policlinico Universitario Campus Bio-Medico, Rome

6229 HX

NOT_YET_RECRUITING

Maastricht University Medical Center, Maastricht

31-913

NOT_YET_RECRUITING

Zeromski hospital, Krakow

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Clinical Trial Unit, University Hospital Basel, Switzerland

OTHER

collaborator

Wuerzburg University Hospital

OTHER

collaborator

Medical University of Vienna

OTHER

collaborator

Videoreha

UNKNOWN

collaborator

University of Oulu

OTHER

collaborator

Theracell Laboratories

UNKNOWN

collaborator

Promove-Biotec GmbH

UNKNOWN

collaborator

Maastricht University

OTHER

collaborator

Foundation National Reumafonds

UNKNOWN

collaborator

Angry@Arthritis

UNKNOWN

collaborator

University of Miami

OTHER

collaborator

Geistlich Pharma AG

INDUSTRY

collaborator

European Union

OTHER

lead

University Hospital, Basel, Switzerland

OTHER