Resonant Frequency rTMS: A Novel Approach to Target Circuit Modulation in Major Depressive Disorder

NAEnrolling by invitationINTERVENTIONAL
Enrollment

84

Participants

Timeline

Start Date

February 12, 2024

Primary Completion Date

October 31, 2028

Study Completion Date

October 31, 2028

Conditions
MDDDepression
Interventions
DEVICE

Transcranial Magnetic Stimulation

Transcranial magnetic stimulation (TMS) is a noninvasive procedure that uses magnetic fields to stimulate nerve cells in the brain to improve symptoms of depression. Using pulsed magnetic fields, transcranial magnetic stimulation therapy stimulates the part of the brain thought to be involved with mood regulation. These magnetic fields do not directly affect the whole brain; they only reach about 2-3 centimeters into the brain directly beneath the treatment coil.As these magnetic fields move into the brain, they produce very small electrical currents. These electrical currents activate cells within the brain, causing them to rewire, a process called neuroplasticity.

Trial Locations (1)

90024

University of California, Los Angeles

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of California, Los Angeles

OTHER