Low EnerGy DiEt iN Adolescents With Obesity and Type 2 Diabetes: The LEGEND Study

NARecruitingINTERVENTIONAL
Enrollment

73

Participants

Timeline

Start Date

June 30, 2025

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Pediatric ObesityType 2 Diabetes
Interventions
DIETARY_SUPPLEMENT

Low-energy diet

For the first 12 weeks during the LED, participants will have 4 meal replacement products each day. The following 12 weeks consists of a gradual reintroduction of food one meal at a time, in a structured stepwise progression, under the supervision of a dietitian. They will then undergo 28 weeks of weight maintenance to see if they are able to keep their weight stable.

OTHER

Qualitive interview - LED participants

Semi-structured interviews with 10 of the LED participants and their relative/carer.

OTHER

Qualitive interview - Participants declining LED

Semi-structured interviews with 10 participants who declined the LED, and their relative/carer.

OTHER

Qualitive interview - Health Care Professionals (HCPs)

Semi-structured interviews with 10 HCPs involved in delivery of the trial.

Trial Locations (1)

NG7 2UH

RECRUITING

Nottingham University Hospital NHS Trust, Nottingham

Sponsors

Collaborators (1)

All Listed Sponsors
collaborator

Diabetes UK

OTHER

lead

Nottingham University Hospitals NHS Trust

OTHER