Evaluation of Dentin Graft and I-PRF With and Without Vitamin C for Post-extraction Socket Preservation

NARecruitingINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

August 1, 2024

Primary Completion Date

February 1, 2025

Study Completion Date

April 1, 2025

Conditions
Socket Preservation
Interventions
PROCEDURE

Alveolar ridge preservation using autogenous demineralized dentin graft and i-PRF

Flapless atraumatic extraction. After thorough mechanical cleaning, the sockets will be rinsed with 5 ml of an aqueous 0.125% chlorhexidine digluconate solution, followed by a 5 ml sterile saline rinse to remove tissue debris from the socket. Followed by inspection of extraction socket integrity, using a William's graduated periodontal probe. Extracted teeth will be cleaned from periodontal ligaments, cementum, soft tissue attachment, caries or restorations using a high-speed fine finishing stone and saline irrigation. The pulp chamber will be cleaned with sterile endodontic files. Teeth will be ground, using hand bone mill.The (ADDG) particles prepared by demineralization of tooth particles in 0.6N hydrochloric acid for 30 min to achieve demineralized then washed twice in saline and dried with sterile gauze. For i-PRF blood will be withdrawn in plastic tubes. The tube will be centrifuged at around 700 RPM for 3 minutes, and extraction socket will be filled with the graft material.

PROCEDURE

Alveolar ridge preservation using vitamin C with dentin graft and i-PRF

Flapless atraumatic extraction. After thorough mechanical cleaning, the sockets will be rinsed with 5 ml of an aqueous 0.125% chlorhexidine digluconate solution, followed by a 5 ml sterile saline rinse to remove tissue debris from the socket. 25mM of pure vitamin C in Fresh blood, and the tube will be centrifuged at around 700 RPM for 3 minutes. Extraction socket will be filled with the corresponding graft material and the dentin graft.

Trial Locations (1)

Unknown

RECRUITING

Faculty of Dentistry, Cairo University, Cairo

All Listed Sponsors
lead

Cairo University

OTHER