Measuring Brain Complexity to Detect and Predict Recovery of Consciousness in the ICU

NARecruitingINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

November 8, 2024

Primary Completion Date

August 31, 2029

Study Completion Date

August 1, 2029

Conditions
Consciousness Disorders
Interventions
OTHER

Repeated behavioral assessments, functional electroencephalography and brain imagery, TMS-EEG

The presence of consciousness will be classified considering the highest level of consciousness revealed by repeated behavioral examinations, functional electroencephalography (task-based EEG), and functional brain imagery (task-based fMRI). Based on the results of this composite standard reference, we will evaluate the diagnostic and prognostic accuracy of TMS-EEG measurements of brain complexity

Trial Locations (2)

53792

NOT_YET_RECRUITING

UW Health University Hospital, Madison

02114

RECRUITING

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

National Institute of Neurological Disorders and Stroke (NINDS)

NIH

lead

Massachusetts General Hospital

OTHER