Early Pharmacological Treatment of Acute Spasticity After Spinal Cord Injury

PHASE4Not yet recruitingINTERVENTIONAL
Enrollment

55

Participants

Timeline

Start Date

December 31, 2024

Primary Completion Date

December 31, 2028

Study Completion Date

June 30, 2029

Conditions
Traumatic Spinal Cord Injury
Interventions
DRUG

Early baclofen Intervention

"Baclofen is initiated as soon as any sign of acute spasticity.~5 mg three times a day and is increased every 7 days by 5 mg per intake (up to a maximum 80 mg total per day) until achieving an optimal response, i.e. when spasticity is no longer problematic."

DRUG

Usual routine care

"Baclofen is initiated only when acute spasticity is deemed problematic.~5 mg three times a day and is increased every 7 days by 5 mg per intake (up to a maximum 80 mg total per day) until achieving an optimal response."

Trial Locations (1)

H4J 1C5

CIUSSS du Nord-de-l'île-de-Montréal-Hôpital du Sacré-Cœur de Montréal, Montreal

All Listed Sponsors
lead

Centre Integre Universitaire de Sante et Services Sociaux du Nord de l'ile de Montreal

OTHER