Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children

NACompletedINTERVENTIONAL
Enrollment

42

Participants

Timeline

Start Date

December 1, 2023

Primary Completion Date

May 31, 2024

Study Completion Date

May 31, 2024

Conditions
Persistent Pulmonary Hypertension of the Newborn
Interventions
DRUG

Sildenafil

Patients were given oral sildenafil as 2 mg per kg per day, 6-hourly with an increment of 0.5 mg per kg per dose and a target maintenance dose of 2 mg per kg per dose every 6 hour by nasogastric tube.

DRUG

Milrinone

In this group, Milrinone was initiated at 0.5 ug per kg per minute using intravenous infusion through a syringe pump, and sildenafil was given in the same protocol mentioned for the Sildenafil Group.

Trial Locations (1)

60000

Children's Hospital and institute of Child Health, Multan

All Listed Sponsors
lead

Muhammad Aamir Latif

OTHER

NCT06562036 - Efficacy of Milrinone With Sildenafil in Persistent Pulmonary Hypertension in Children | Biotech Hunter | Biotech Hunter