Effect of L. Plantarum Probiotic Supplementation on Broccoli Sulforaphane Bioavailability: Randomised Double-blind Placebo-controlled Crossover Study

NAActive, not recruitingINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

July 31, 2025

Study Completion Date

January 31, 2026

Conditions
Nutrition, Healthy
Interventions
DIETARY_SUPPLEMENT

Broccoli sprouts extract supplementation

Intake of broccoli sprouts extract supplement (Brand: Source Naturals, Scotts Valley, CA 95066 - USA) in an acute dose (84 umol of glucoraphanin) before and after 2 weeks of probiotic or placebo supplementation, to assess sulforaphane bioavailability measured in urine metabolites

Trial Locations (2)

EX1 2 LU

The Department of Public Health and Sport Sciences, University of Exeter Medical School, Faculty of Health and Life Sciences, University of Exeter, Exeter

EX2 4TA

Richard's Building, St Luke's Campus, Exeter

All Listed Sponsors
collaborator

The University of Queensland

OTHER

collaborator

PepsiCo, Inc.

INDUSTRY

lead

University of Exeter

OTHER