NCT06561828View on ClinicalTrials.gov

Developing Transcranial Neuromodulation Protocols for Learning and Decision-Making

EARLY_PHASE1RecruitingINTERVENTIONAL
Enrollment

600

Participants

Timeline

Start Date

October 28, 2025

Primary Completion Date

November 1, 2044

Study Completion Date

November 2, 2044

Conditions
Normal Physiology
Interventions
DEVICE

continuous Theta Burst Stimulation (cTBS)

Continuous theta burst stimulation (three TMS pulses delivered at 50Hz with the bursts delivered at 5Hz for a total of 600 pulses per site).

DEVICE

intermittent Theta Burst Stimulation (iTBS)

Intermittent theta burst stimulation (three TMS pulses delivered at 50Hz with the bursts delivered at 5Hz for 2 seconds followed by a break of 8 seconds for a total of 600 pulses per site).

DEVICE

sham Theta Burst Stimulation (sham TBS)

iTBS or cTBS delivered with placebo side of A/P coil.

Trial Locations (1)

21224

RECRUITING

National Institute on Drug Abuse, Baltimore

All Listed Sponsors
lead

National Institute on Drug Abuse (NIDA)

NIH