NCT06558799 - LUNAR-4: Effect of Tumor Treating Fields (TTFields) (150 kHz) Concurrent With Pembrolizumab for Treatment of Metastatic Non-small Cell Lung Cancer (NSCLC) | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

October 14, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions

Non-Small Cell Lung Cancer (NSCLC)

Interventions

DEVICE

NovoTTF-200T

The NovoTTF-200T is a portable, battery operated system intended for continuous home use, which delivers TTFields at a frequency of 150kHz to the subject by means of insulated transducer arrays. TTFields exert electric forces intended to disrupt cancer cell division and induce immunogenic cell death.

DRUG

Pembrolizumab

Pembrolizumab is an immune checkpoint inhibitor that helps the immune system recognize and attack cancer cells.

Trial Locations (24)

1192

RECRUITING

Vitkovicka Nemocnice, Ostrava

13003

RECRUITING

Hôpital Européen Marseille, Marseille

20141

RECRUITING

Istituto Europeo di Oncologia, Milan

28027

RECRUITING

Clínica Universidad de Navarra, Madrid, Madrid

29107

RECRUITING

Centre Hospitalier Intercommunal de Cornouaille Service D'oncologie Médicale, Quimper

31008

RECRUITING

Clínica Universidad de Navarra, Pamplona

34295

RECRUITING

Montpellier University Hospital, Montpellier

44277

RECRUITING

Hôpital Privé du Confluent Service D'oncologie Médicale, Nantes

53100

RECRUITING

AOUS Policlinico Le Scotte U.O.C. Immunoterapia Oncologica, Siena

69373

RECRUITING

Centre Léon Berard Service D'oncologie Médicale, Lyon

92100

RECRUITING

APHP - Hôpital Ambroise-Paré, Boulogne-Billancourt

94010

RECRUITING

Centre hospitalier intercommunal de Créteil Service de Pneumologie, Créteil

Unknown

RECRUITING

Universitätsklinik f. Innere Medizin III, Salzburg

RECRUITING

Humanitas Gavazzeni Bergamo-U.O.Farmacia-Edificio D Piano -1, Bergamo

RECRUITING

Rijnstate Ziekenhuis, Arnhem

RECRUITING

Pratia MCM Kraków, Krakow

RECRUITING

MS Pneumed Janusz Milanowski, Katarzyna Szmygin-Milanowska Spó?ka Jawna, Lublin

RECRUITING

Hospital Universitario Arnau de Vilanova, Lleida

RECRUITING

Hospital Regional Universitario de Malaga (Hospital Civil), Málaga

RECRUITING

Hospital Universitario Virgen del Rocio, Seville

128 08

RECRUITING

General University Hospital in Prague, Clinic of Oncology, Prague

150 06

RECRUITING

FN Motol, Prague

06129

RECRUITING

AO SM Misericordia di Perugia, Perugia

03293

RECRUITING

Hospital Universitario del Vinalopó, Elche

All Listed Sponsors

lead

NovoCure GmbH

INDUSTRY