550
Participants
Start Date
December 12, 2024
Primary Completion Date
June 30, 2027
Study Completion Date
March 31, 2033
Any commercially available transcatheter aortic valve
Redo TAVI will be performed using any commercially available transcatheter aortic valve according to the preferences of the local team in keeping with standard clinical care.
Surgical explantation and aortic valve replacement
Surgical explantation and aortic valve replacement will be performed according to the preferences of the local team in keeping with standard clinical care. Any commercially available approved surgical aortic valve may be used. Additional surgery, such as aortic root replacement, root enlargement, CABG, mitral valve repair/replacement, etc. will be performed at the discretion of the local team.
Conservative management
Conservative treatment, including optimal medical therapy +/- balloon aortic valvuloplasty
RECRUITING
Århus Universitetshospital, Aarhus
RECRUITING
Rigshospitalet, Copenhagen
RECRUITING
HUS Helsinki University Hospital, Helsinki
RECRUITING
Turku University Hospital, Turku
RECRUITING
Maastricht University Medical Center (MUMC), Maastricht
RECRUITING
Erasmus University Medical Center, Rotterdam
RECRUITING
Haukeland Sykehus, Bergen
RECRUITING
Oslo University Hospital, Oslo
RECRUITING
Sahlgrenska University Hospital, Gothenburg
RECRUITING
Inselspital - Universitätsspital Bern, Bern
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Luzerner Kantonsspital, Lucerne
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Bristol Royal Infirmary, Bristol
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Golden Jubilee National Hospital, Glasgow
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St. George's Hospital, London
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Freeman Hospital, Newcastle upon Tyne
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New Cross Hospital, Wolverhampton
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Royal Sussex County Hospital, Brighton
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University Hospital of Wales, Cardiff
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Leeds Teaching Hospitals NHS Trust, Leeds
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Oxford University Hospitals NHS Foundation Trust, Oxford
RECRUITING
University Hospital Southampton NHS Foundation Trust, Southampton