Anastomotic Leaks in Esophageal Squamous Cell Carcinoma Patients After Trimodal Therapy

CompletedOBSERVATIONAL
Enrollment

218

Participants

Timeline

Start Date

November 1, 2022

Primary Completion Date

September 15, 2023

Study Completion Date

September 15, 2023

Conditions
Anastomotic Leak Esophagus
Interventions
OTHER

neoadjuvant chemoradiation and McKeown esophagectomy

"Treatment protocol:~1. All patients were irradiated a total prescribed dose of 40-50.4 Gy in 20-28 fractions by a 6-8 MV photons linear accelerator with the intensity-modulated radiotherapy or volumetric modulated arc therapy technique.~2. Concurrent chemotherapy was cisplatin-based.~3. McKeown esophagectomy (three incision) consisted of thoracic esophageal mobilization with lymphadenectomy, abdominal exploration and stomach mobilization with lymphadenectomy, and subsequently left cervical incision for anastomosis. The lymphadenectomy was total two-field (thoracic + abdomen)."

Trial Locations (1)

510060

Sun Yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
collaborator

Chinese Institute of Food Science and Technology

UNKNOWN

lead

Qiaoqiao Li

OTHER