Human Amniotic Mesenchymal Cell Secretome for Neurodegeneration and Neuroinflammation

NARecruitingINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

January 17, 2025

Primary Completion Date

March 31, 2026

Study Completion Date

September 30, 2026

Conditions
Amyotrophic Lateral SclerosisMultiple Sclerosis
Interventions
OTHER

Venous blood draw and skin biopsy

The skin tissue will be used to isolate fibroblasts, which will then be reprogrammed into induced pluripotent stem cells (iPSCs). These iPSCs will be differentiated to develop patient-specific and control organoids. The blood samples will be used to isolate peripheral blood mononuclear cells (PBMC) to study the contribution of inflammation in the in vitro models developed.

Trial Locations (2)

00168

NOT_YET_RECRUITING

Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma

RECRUITING

Fondazione Policlinico Universitario Agostino Gemelli IRCCS, Rome

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER