Treatment of ELectroencephalographic STatus Epilepticus After Cardiopulmonary Resuscitation-2 (TELSTAR-2)

NARecruitingINTERVENTIONAL
Enrollment

150

Participants

Timeline

Start Date

April 10, 2025

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2030

Conditions
ComaElectrographic Status Epilepticus
Interventions
DRUG

anti-seizure medication + sedative agent(s)

"Stepwise approach:~1. a single dose of a parenteral benzodiazepine (lorazepam, midazolam, or diazepam) and a first parenteral anti-seizure medication (levetiracetam, valproate, or lacosamide)~2. a second parenteral anti-seizure medication plus a first continuous parenteral sedative agent (midazolam or propofol)~3. a second continuous parenteral sedative agent (midazolam, propofol, or ketamine)"

Trial Locations (20)

Unknown

NOT_YET_RECRUITING

Centre Hospitalier Universitaire Saint-Pierre, Brussels

NOT_YET_RECRUITING

Hôpital Universitaire de Bruxelles, Brussels

NOT_YET_RECRUITING

Universitair Ziekenhuis Brussel, Brussels

NOT_YET_RECRUITING

Centre Hospitalier Universitaire Marie Curie, Charleroi

NOT_YET_RECRUITING

Ziekenhuis Oost-Limburg, Genk

NOT_YET_RECRUITING

Universitair Ziekenhuis Gent, Ghent

NOT_YET_RECRUITING

Centre Hospitalier Chrétien - MontLégia, Liège

NOT_YET_RECRUITING

Centre Hospitalier Universitaire Sart-Tilmant, Liège

NOT_YET_RECRUITING

Amsterdam University Medical Center, Amsterdam

RECRUITING

Rijnstate Hospital, Arnhem

NOT_YET_RECRUITING

Catharina Hospital, Eindhoven

RECRUITING

Medical Spectrum Twente, Enschede

NOT_YET_RECRUITING

University Medical Center Groningen, Groningen

NOT_YET_RECRUITING

Leiden University Medical Center, Leiden

RECRUITING

St. Antonius Hospital, Nieuwegein

NOT_YET_RECRUITING

Canisius Wilhelmina Hospital, Nijmegen

RECRUITING

Radboud University Medical Center, Nijmegen

RECRUITING

Erasmus University Medical Center, Rotterdam

NOT_YET_RECRUITING

Maasstad Hospital, Rotterdam

NOT_YET_RECRUITING

VieCuri Medical Center, Venlo

All Listed Sponsors
collaborator

Hôpital Universitaire de Bruxelles

UNKNOWN

collaborator

ZonMw: The Netherlands Organisation for Health Research and Development

OTHER

collaborator

Belgium Health Care Knowledge Centre

OTHER_GOV

lead

University of Twente

OTHER