Early Antiplatelet Administration After Intravenous Thrombolysis for Acute Ischemic Stroke (TREND-IVT)

PHASE3RecruitingINTERVENTIONAL
Enrollment

1,184

Participants

Timeline

Start Date

November 7, 2024

Primary Completion Date

March 31, 2026

Study Completion Date

March 31, 2026

Conditions
Acute Ischemic StrokeCerebral Infarction
Interventions
DRUG

Aspirin

Patients in the interventional group will chew 300mg of aspirin enteric-coated tablets as soon as possible after randomization. If swallowing difficulties arise, the tablets can be crushed and administered via a nasogastric tube.

DRUG

Placebo

Patients in the control group will chew 300mg of placebos as soon as possible after randomization. If swallowing difficulties arise, the placebo can be crushed and administered via a nasogastric tube.

OTHER

Best medical management

Patients in both groups will receive the best medical management according to the guidelines.

Trial Locations (23)

100053

RECRUITING

Xuanwu Hospital, Capital Medical University, Beijing

161005

NOT_YET_RECRUITING

The First Hospital Of Qiqihar, Qiqihar

162650

RECRUITING

Zha Lan Tun Shi Zhong Meng Yi Yuan, Zhalantun

233000

NOT_YET_RECRUITING

The Third The People's Hospital Of Bengbu, Bengbu

250101

NOT_YET_RECRUITING

Jinan Third People's Hospital, Jinan

252000

RECRUITING

The Third People Hospital In Liaocheng, Liaocheng

264200

RECRUITING

Weihai Municipal Hospital, Weihai

314311

RECRUITING

Haiyan People's Hospital, Jiaxing

330008

NOT_YET_RECRUITING

The Second Affiliated Hospital Of Nanchang University, Nanchang

333000

RECRUITING

Jingdezhen NO.1 People's Hospital, Jingdezhen

361003

NOT_YET_RECRUITING

The First Affiliated Hospital Of Xiamen University, Xiamen

401121

RECRUITING

The First Affiliated Hospital of Chongqing Medical and Pharmaceutical College, Chongqing

410300

RECRUITING

Liuyang Jili Hospital, Guankou

411100

RECRUITING

Xiangtan Central Hospital, Xiangtan

412007

NOT_YET_RECRUITING

Zhuzhou Central Hospital, Zhuzhou

466000

NOT_YET_RECRUITING

Xihua People's Hospital, Zhoukou

471900

RECRUITING

Luoyang Yanshi People's Hospital, Luoyang

535099

NOT_YET_RECRUITING

The Second People's Hospital Of Qinzhou, Qinzhou

543002

NOT_YET_RECRUITING

Wuzhou Red Cross Hospital, Wuzhou

614000

NOT_YET_RECRUITING

The People's Hospital Of Leshan, Leshan

832000

NOT_YET_RECRUITING

Shihezi City People's Hospital, Shihezi

028007

RECRUITING

Affiliated Hospital of Inner Mongolia University for the Nationalities, Tongliao

012000

NOT_YET_RECRUITING

Ulanqab Central Hospital, Ulanqab

All Listed Sponsors
lead

Capital Medical University

OTHER