NCT06544798 - Long-term Follow-up of Gene Therapy for Radiation-Induced Xerostomia | Biotech Hunter

Enrollment

276

Participants

Timeline

Start Date

August 2, 2024

Primary Completion Date

February 29, 2032

Study Completion Date

February 29, 2032

Conditions

Grade 2 and 3 Late Xerostomia Caused by Radiotherapy for Cancers of the Upper Aerodigestive Tract, Excluding the Parotid Glands

Interventions

GENETIC

AAV2-hAQP1

Administration of a prespecified concentration of AAV2-hAQP1 via Stensen's duct to each parotid gland

Trial Locations (8)

Erie County Medical Center, Buffalo

Alleghany General Hospital, Pittsburgh

Atrium Health, Charlotte

Miami Cancer Institute at Baptist Health South Florida, Miami

University of Iowa, Iowa City

University of Missouri, Columbia

Banner MD Anderson Cancer Center, Gilbert

Shirley and Jim Fielding Northeast Cancer Centre - Health Sciences North, Greater Sudbury