Elimination of PTV Margins Based on Online Adaptive Stereotactic Radiotherapy for Early-stage Non-small Cell Lung Cancer or Pulmonary Oligometastases

PHASE2RecruitingINTERVENTIONAL
Enrollment

130

Participants

Timeline

Start Date

May 22, 2024

Primary Completion Date

April 21, 2027

Study Completion Date

April 21, 2028

Conditions
Adaptive RadiotherapyStereotactic Body RadiotherapyNon-small Cell Lung CancerLung OligometastasesToxicity
Interventions
RADIATION

Online adaptive SBRT

Online adaptive SBRT (without PTV expansion margin). The total dose will be 45-50Gy/3-4 fractions, administered once daily. FBCT and 4DCT will be acquired.

RADIATION

Conventional SBRT

SBRT with PTV expansion. The total dose will be 45-50Gy/3-4 fractions, administered once daily. CBCT will be acquired.

Trial Locations (1)

510060

RECRUITING

Sun yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER