Iodine Supplementation in Graves' Hyperthyroidism

NANot yet recruitingINTERVENTIONAL
Enrollment

315

Participants

Timeline

Start Date

August 1, 2024

Primary Completion Date

July 31, 2027

Study Completion Date

July 31, 2028

Conditions
Graves DiseaseHyperthyroidism
Interventions
DIETARY_SUPPLEMENT

Iodine Supplementation in Whole Course of Treatment with ATDs

Moderate iodine supplementation (150μg iodine per day, equivalently 7-9g iodized salt per day) will be taken from ATDs treatment starting until 1 year after ATDs withdrawal.

DIETARY_SUPPLEMENT

Iodine Supplementation During Maintenance Treatment with ATDs

Iodine restriction (non-iodized salt and low iodine diet) will be demanded at the early course of ATDs treatment, and moderate iodine supplementation (150μg iodine per day, equivalently 7-9g iodized salt per day) will be taken when the ATDs dose is titrated down to a maintenance level until 1 year after ATDs withdrawal.

DIETARY_SUPPLEMENT

Iodine Restriction in Whole Course of Treatment with ATDs

Iodine restriction (non-iodized salt and low iodine diet) will be demanded from ATDs treatment starting until 1 year after ATDs withdrawal.

DRUG

anti-Thyroid Drugs

Individualized methimazole (MMI)

All Listed Sponsors
collaborator

First Hospital of China Medical University

OTHER

collaborator

The Second Affiliated Hospital of Harbin Medical University

OTHER

lead

Shandong Provincial Hospital

OTHER_GOV

NCT06540469 - Iodine Supplementation in Graves' Hyperthyroidism | Biotech Hunter | Biotech Hunter