366
Participants
Start Date
August 1, 2024
Primary Completion Date
June 30, 2026
Study Completion Date
July 30, 2026
Sedation with Ciprofol
During the drug administration period, ciprofol were IV infused at loading doses of 0.1 mg/kg, respectively, over 4 minutes ± 30 seconds depending on the physical condition of each patient. Ciprofol were then immediately administered at an initial maintenance dose of 0.3 mg/kg/hr, with a target sedation depth of RASS +1 to -2, based on the Pain, Agitation/sedation, Delirium, Immobility (rehabilitation/mobilization), and Sleep (disruption) guideline.
Sedation with Propofol
During the drug administration period, propofol were IV infused at loading doses of 0.5 mg/kg, respectively, over 4 minutes ± 30 seconds depending on the physical condition of each patient. Propofol were then immediately administered at an initial maintenance dose of 1.5 mg/kg/hr, with a target sedation depth of RASS +1 to -2, based on the Pain, Agitation/sedation, Delirium, Immobility (rehabilitation/mobilization), and Sleep (disruption) guideline.
The First Affiliated Hospital of Air Force Medicial University
OTHER
First Affiliated Hospital, Sun Yat-Sen University
OTHER
Zhongnan University Xiangya Second Hospital
UNKNOWN
Renmin Hospital of Wuhan University
OTHER
First Affiliated Hospital of Suzhou Medical College
OTHER
The First Affiliated Hospital of Nanchang University
OTHER
The Third Bethune Hospital of Jilin University
UNKNOWN
Zhongnan Hospital
OTHER
First Affiliated Hospital of the University of Science and Technology of China (Anhui Provincial Hospital)
UNKNOWN
First Affiliated Hospital of the Xi'an Jiaotong University
UNKNOWN
First Affiliated Hospital of Kunming Medical University
OTHER
Sichuan Academy of Medical Sciences
OTHER
Anhui provincial chest hospital
UNKNOWN
The Guangxi Zhuang Autonomous Region People's Hospital
UNKNOWN
Second Affiliated Hospital of Suzhou University
OTHER
The Ninth People's Hospital of Suzhou
UNKNOWN
Fifth Affiliated Hospital of Xinjiang Medical University
OTHER
Xuzhou Medical University Hospital
UNKNOWN
First People's Hospital of Hangzhou
OTHER
Hebei Medical University Fourth Hospital
OTHER
Huai'an First People's Hospital
OTHER
Jinan City People's Hospital
UNKNOWN
The First People's Hospital of Lianyungang
OTHER
Jiangsu Subei People's Hospital
UNKNOWN
Suqian First Hospital
OTHER
Tai'an City Central Hospital
UNKNOWN
Xuzhou Central Hospital
OTHER
The first People's Hospital of Yancheng City
UNKNOWN
The First People's Hospital of Zunyi
OTHER
Jiangxi Provincial People's Hopital
OTHER
Henan Provincial People's Hospital
OTHER
Zhongda Hospital
OTHER