Impact of High Versus Lower Oxygen Fraction Prior to Extubation on Postoperative Pulmonary Atelectasis Measured With EIT

NACompletedINTERVENTIONAL
Enrollment

48

Participants

Timeline

Start Date

September 27, 2024

Primary Completion Date

May 15, 2025

Study Completion Date

May 22, 2025

Conditions
Atelectasis
Interventions
PROCEDURE

Ventilating the patient with lower (40 or 70%) oxygen concentration during the wash out phase, before extubation

The investigated intervention is the application of 70% inspired oxygen compared to 100% inspired oxygen during the anesthetic washout, right before extubation of the patient for the first 24 enrolled patients, and 40% inspired oxygen compared to 100% inspired oxygen for the subsequently enrolled 24 patients. Before and after the intervention EIT measurements are performed at designated time points to assess lung aeration and calculate the center of ventilation. This information allows assumptions on atelectasis formation in the patients' lung.

Trial Locations (1)

02215

Department of Anesthesia, Critical Care and Pain Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston

All Listed Sponsors
lead

Beth Israel Deaconess Medical Center

OTHER

NCT06538740 - Impact of High Versus Lower Oxygen Fraction Prior to Extubation on Postoperative Pulmonary Atelectasis Measured With EIT | Biotech Hunter | Biotech Hunter