The Crosstalk Between the Epigenome and Mitochondria in SCI

Not yet recruitingOBSERVATIONAL
Enrollment

50

Participants

Timeline

Start Date

August 30, 2024

Primary Completion Date

August 30, 2025

Study Completion Date

August 30, 2026

Conditions
Injury, Spinal Cord
Interventions
OTHER

Data collection

"The data to be collected are the following:~* Demographic data: gender and age of the patient at diagnosis of SCI;~* Drug assumption and drug abuse at the time of SCI;~* A complete assessment of patients' comorbidities;~* Complete neurological examination on admission and at 6-8 months follow-up according to ASIA protocol;~* Neuro-radiological data: spinal CT and MRI performed within 48 hours of admission to document the type, level and extent of the lesion of the spine and the spinal cord;~* CSF pressure, chemical and biological markers;~* Serum chemical and biological markers;~* Data coming from surgical procedure: type of decompression, type of stabilization, extension of the stabilization, surgical approach, staged surgery, timing of surgery, length of surgery, eventual intraoperative, postoperative or long-term surgical-related complications \[13\];~* Data on hospitalization: length of stay, hospital-acquired infections, any adverse event occurred during hospitalisation."

All Listed Sponsors
lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

NCT06537427 - The Crosstalk Between the Epigenome and Mitochondria in SCI | Biotech Hunter | Biotech Hunter