The Effects Of Therapeutic Plasma Exchange (TPE) On Age Related Biomarkers And Epigenetics

PHASE3Active, not recruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

September 12, 2022

Primary Completion Date

November 30, 2023

Study Completion Date

August 31, 2025

Conditions
Aging
Interventions
DEVICE

Sham

The patient's blood will not circulate through the apheresis machine. The patient will receive approximately 250 cc of normal saline during each sham pheresis procedure.

DEVICE

Therapeutic Plasma Exchange

Blood is withdrawn from a peripheral or central vein into the blood cell separator which separates the whole blood into plasma and cell components. The plasma is removed and the blood cells are returned to the patient along with replacement fluids, most commonly 5% human albumin in normal saline.

DRUG

IVIG

Intravenous Immunoglobulin

Trial Locations (1)

94941

Global Apheresis, Mill Valley

All Listed Sponsors
collaborator

CIRCULATE, Inc.

UNKNOWN

lead

Dobri Kiprov

INDUSTRY