Endoscopic Surgery vs. Intensity Modulated Radiotherapy for Stage I Nasopharyngeal Carcinoma.

NARecruitingINTERVENTIONAL
Enrollment

442

Participants

Timeline

Start Date

March 25, 2024

Primary Completion Date

March 25, 2034

Study Completion Date

March 25, 2034

Conditions
Nasopharyngeal CarcinomaIntensity Modulated RadiotherapySurgery
Interventions
PROCEDURE

Endoscopic nasopharyngectomy followed close follow-up

"Radical resection of primary lesion using nasal endoscopy.~After the treatment, the electronic nasal endoscopy was reviewed every two weeks to determine the healing of the wound, whether there was tumor recurrence, until the surgical wound was completely healed. The patients were followed up at least once every three months from the first year to the third year, at least once every six months from the fourth year to the fifth year, and at least once every year after five years."

RADIATION

Intensity-modulated Radiotherapy

"GTVnx (nasopharyngeal lesions): 69.96Gy/33Fr/2.12Gy CTV1: 60.60Gy/33Fr/1.82Gy CTV2: 54.12Gy/33Fr/1.64Gy.~After treatment, patients were followed up every 3-6 months from the first year to the third year, every 6-12 months from the fourth year to the fifth year, and at least once a year after five years."

Trial Locations (1)

519000

RECRUITING

The Fifth Affiliated Hospital of Sun Yat-sen University, Zhuhai

All Listed Sponsors
collaborator

Fifth Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Fifth Affiliated Hospital of Guangzhou Medical University

OTHER

collaborator

Huazhong University of Science and Technology Union ShenZhen Hospital (Nanshan Hospital)

UNKNOWN

collaborator

First Affiliated Hospital, Sun Yat-Sen University

OTHER

collaborator

Nanfang Hospital, Southern Medical University

OTHER

collaborator

First People's Hospital of Foshan

OTHER

collaborator

Zhongshan People's Hospital, Guangdong, China

OTHER

lead

Sun Yat-sen University

OTHER