Comparison of Early Proton Pump Inhibitor Initiation Versus Usual Care on Acute Kidney Injury in Hemorrhagic Shock Patients

PHASE2/PHASE3RecruitingINTERVENTIONAL
Enrollment

100

Participants

Timeline

Start Date

September 7, 2024

Primary Completion Date

July 31, 2025

Study Completion Date

July 31, 2025

Conditions
Acute Kidney Injury
Interventions
DRUG

Protonix (Pantoprazole) 40 mg q 12 hrs for 2 days

Within 2 hours of ED admission after inclusion criteria is met, administer 1st dose of Protonix (pantoprazole) 40mg, then followed by 40mg q12hrs for 2 additional days.

DRUG

Protonix (pantoprazole) 40 mg q 24 hrs for 2 days

Administer 1st dose of 40mg Protonix (pantoprazole) at the usual timing (current practice: in the intensive care unit), then followed by 40mg daily for 2 additional days.

Trial Locations (1)

77030

RECRUITING

Memorial Hermann Texas Medical Center, Houston

All Listed Sponsors
collaborator

The University of Texas Health Science Center at San Antonio

OTHER

lead

The University of Texas Health Science Center, Houston

OTHER