Adebelimab Combined With Irinotecan Liposomal Injection, Oxaliplatin, Fluorouracil and Calcium Folinate Are Used in the First-line Treatment of Pancreatic Cancer Liver Metastasis Efficacy and Safety

PHASE2RecruitingINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

July 16, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Pancreatic Cancer Metastatic to Liver
Interventions
DRUG

Irinotecan liposome

"* Patients are planned to receive irinotecan liposomal (60 mg/m2; d1) of every cycle.~* 27 days a cycle"

DRUG

Adebrelimab

"* Patients are planned to receive Adebrelimab (20 mg/kg; d1) of every cycle.~* 27 days a cycle"

DRUG

Oxaliplatin

"* Patients are planned to receive Oxaliplatin (85 mg/m2; d1) of every cycle.~* 27 days a cycle"

DRUG

Fluorouracil

"* Patients are planned to receive fluorouracil (2400mg/m2; d1) of every cycle.~* 27 days a cycle"

DRUG

Calcium folinate

"* Patients are planned to receive Calcium folinate (400mg/m2; d1) of every cycle.~* 27 days a cycle"

Trial Locations (1)

200040

RECRUITING

Shanghai General Hospital, Shanghai

All Listed Sponsors
lead

Jiang Long

OTHER