NCT06529913View on ClinicalTrials.gov

Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases

NANot yet recruitingINTERVENTIONAL
Enrollment

280

Participants

Timeline

Start Date

October 1, 2024

Primary Completion Date

May 31, 2025

Study Completion Date

December 31, 2026

Conditions
Allergic Contact DermatitisMetal AllergyFood AllergyNickel SensitivityNickel; EczemaAluminum AllergyChromium; EczemaFunctional Gastrointestinal DisordersRespiratory InjuryPollution; ExposurePollution Related Respiratory DisorderEnvironmental ExposureEnvironment Related DiseaseEnvironmental IllnessOxidative StressRisk Reduction
Interventions
DIAGNOSTIC_TEST

Collection of environmental, biological, and clinical data

"All enrolled patients/healthy volunteers will undergo:~* measurement of serum and urine concentration of metals (nickel, cobalt, chromium, palladium, molybdenum, aluminium, and copper).~* Patch test to metals.~* Within-breath analysis of oscillometry parameters.~* Measurement of serum zonulin.~* Measurement of serum levels of protein oxidation products."

Trial Locations (2)

40126

Università di Bologna, Bologna

00168

Fondazione Policlinico Universitario A. Gemelli IRCCS, Roma

All Listed Sponsors
collaborator

University of Bologna

OTHER

lead

Fondazione Policlinico Universitario Agostino Gemelli IRCCS

OTHER

NCT06529913 - Environmental Exposure to Heavy Metals, Nanoparticles, and Emergent Contaminants and Risk of Allergic Diseases | Biotech Hunter | Biotech Hunter