Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION)

NANot yet recruitingINTERVENTIONAL
Enrollment

180

Participants

Timeline

Start Date

September 1, 2025

Primary Completion Date

June 14, 2027

Study Completion Date

June 14, 2027

Conditions
Chronic Ankle Instability
Interventions
OTHER

Neurocognitive Ankle Training for Instablity to Optimize Neuromusculoskeletal outcomes (NATION)

The NATION rehabilitation protocol will serve as the true intervention group. NATION is a 6-week evidence-based chronic ankle instability (CAI) rehabilitation protocol that incorporates neurocognitive exercises. Participants will complete up to 18 unsupervised home sessions and up to 12 supervised sessions. Treatment volume and exercises may vary based on participant progress and study team member guidance.

OTHER

Evidence-Based

The Evidence-Based rehabilitation protocol will serve as the active comparator group. The Evidence-Based protocol will be similar to the intervention (i.e., NATION protocol), but the exercises will exclude the neurocognitive tasks. Participants assigned to the Evidence-Based protocol will complete up to 18 unsupervised home sessions and up to 12 supervised sessions over the course of 6-weeks. Treatment volume and exercises may vary based on participant progress.

All Listed Sponsors
collaborator

University of Kentucky

OTHER

lead

Womack Army Medical Center

FED

NCT06527287 - Neurocognitive Ankle Training for Instability to Optimize Neuromusculoskeletal Outcomes (NATION) | Biotech Hunter | Biotech Hunter