Meniscal INfiltration of Corticosteroid Guided with Ultra Sonography

PHASE3Not yet recruitingINTERVENTIONAL
Enrollment

152

Participants

Timeline

Start Date

March 1, 2025

Primary Completion Date

June 1, 2028

Study Completion Date

June 1, 2028

Conditions
Meniscus Lesion
Interventions
DRUG

ultrasound-guided betamethasone infiltration of the meniscal wall

The perimeniscal injections will be guided by ultrasound with an 18 megahertz (MHz) linear probe under strict aseptic conditions. Doppler will be systematically used before the injection to identify the medial or lateral inferior geniculate artery. The first step will consist of local anesthesia with 2 ml of lidocaine injected into the subcutaneous tissues and close to the meniscus wall using a 25-gauge needle. Using an in-plane approach, a 21-gauge needle will be positioned under ultrasound guidance in the medial or lateral wall of the meniscus. Once the needle touches the meniscus wall, it will be withdrawn 1 mm, and a 1-ml injection of betamethasone into the meniscus wall will be performed.

DRUG

ultrasound-guided isotonic saline (placebo) infiltration of the meniscal wall

The perimeniscal injections will be guided by ultrasound with an 18 MHz linear probe under strict aseptic conditions. Doppler will be systematically used before the injection to identify the medial or lateral inferior geniculate artery. The first step will consist of local anesthesia with 2 ml of isotonic saline injected into the subcutaneous tissues and close to the meniscus wall using a 25-gauge needle. Using an in-plane approach, a 21-gauge needle will be positioned under ultrasound guidance in the medial or lateral wall of the meniscus. Once the needle touches the meniscus wall, it will be withdrawn 1 mm, and a 1-ml injection of betamethasone into the meniscus wall will be performed.

All Listed Sponsors
lead

University Hospital, Toulouse

OTHER