Interest of Post-operative Chemotherapy in Patients With Localised Uterine Leiomyosarcoma Suspected of Having a High Risk of Recurrence Based on a Biological Test Performed on the Tumour

PHASE2RecruitingINTERVENTIONAL
Enrollment

198

Participants

Timeline

Start Date

January 27, 2025

Primary Completion Date

December 31, 2029

Study Completion Date

December 31, 2030

Conditions
Leiomyosarcoma Uterus
Interventions
DRUG

Doxorubicin

60 mg/m² intravenous (IV) at Day 1 every 3 weeks (4 cycles)

DRUG

Trabectedin

1.1 mg/m² intravenous (IV) at Day 1 every 3 weeks (4 cycles)

Trial Locations (25)

13273

NOT_YET_RECRUITING

Institut Paoli Calmettes, Marseille

13385

RECRUITING

La Timone University Hospital, Marseille

14176

NOT_YET_RECRUITING

Centre Francois Baclesse, Caen

21079

NOT_YET_RECRUITING

Centre Georges Francois Leclerc, Dijon

25030

NOT_YET_RECRUITING

Hopital Jean Minjoz, Besançon

31052

NOT_YET_RECRUITING

Institut Claudius Regaud, Toulouse

33076

NOT_YET_RECRUITING

Institut Bergonie, Bordeaux

35042

NOT_YET_RECRUITING

Centre Eugene Marquis, Rennes

37000

NOT_YET_RECRUITING

CHU Bretonneau, Tours

44805

NOT_YET_RECRUITING

Institut de cancerologie de l'ouest site Rene Gauducheau, Saint-Herblain

49100

NOT_YET_RECRUITING

Institut de Cancerologie de L'Ouest (Ico), Angers

54519

NOT_YET_RECRUITING

Centre Alexis Vautrin, Vandœuvre-lès-Nancy

63011

NOT_YET_RECRUITING

Centre Jean Perrin, Clermont-Ferrand

69373

NOT_YET_RECRUITING

Centre Léon Berard, Lyon

75010

NOT_YET_RECRUITING

Hopital Saint Louis, Paris

75014

NOT_YET_RECRUITING

Hôpital Cochin, Paris

75020

NOT_YET_RECRUITING

Groupe Hospitalier Diaconesses Croix St Simon, Paris

NOT_YET_RECRUITING

Hopital Tenon, Paris

76038

NOT_YET_RECRUITING

Centre Henri Becquerel, Rouen

86000

NOT_YET_RECRUITING

Chu de Poitiers, Poitiers

87042

NOT_YET_RECRUITING

Chu Limoges, Limoges

94800

RECRUITING

Gustave Roussy, Villejuif

06189

NOT_YET_RECRUITING

Centre Antoine Lacassagne, Nice

Unknown

NOT_YET_RECRUITING

Institut Curie, Paris

NOT_YET_RECRUITING

Institut de Cancerologie Strasbourg Europe (Icans), Strasbourg

Sponsors
All Listed Sponsors
collaborator

PharmaMar

INDUSTRY

collaborator

Ligue contre le cancer, France

OTHER

collaborator

National Research Agency, France

OTHER

collaborator

University Hospital, Marseille

OTHER

collaborator

Institut Claudius Regaud

OTHER

collaborator

Institut Bergonié

OTHER

collaborator

Oncopole

UNKNOWN

lead

UNICANCER

OTHER