Preoperative Corneal Measurements Estimate the Corrected Distance Visual Acuity After Corneal Cross-linking

NACompletedINTERVENTIONAL
Enrollment

124

Participants

Timeline

Start Date

April 1, 2018

Primary Completion Date

July 30, 2022

Study Completion Date

July 30, 2023

Conditions
Keratoconus
Interventions
PROCEDURE

corneal cross-linking procedure

Standard Dresden protocol corneal cross-linking procedure The CXL procedure adhered to the standard Dresden protocol. All patients received topical anaesthetic (Tetracaine HCL 0.5%, Alcon Forth Worth, Texas) and a miotic (Isopto Carpine 2% HCl, Alcon, Fort Worth, Texas) drops 30 minutes before the procedure. The periocular region and conjunctival sac were washed with 10% povidone-iodine (Betadine 10%, Alcaloid, Skopje). Manual epithelial scraping with a crescent knife followed. Pachymetry was kept over 400 μm during the procedure and measured with an ultrasound hand pachymeter (Pocket II, Quantel Medical, Cournon d'Auvergne, France). Riboflavin (Peschke D, Peschke Trade, Huenenberg, Switzerland) was applied every 3 minutes for 30 minutes. We performed corneal UV-A radiation with a wavelength of 370 nm and energy of 3mW using a UVA CXL lamp (VEGA CBM-X-Linker, Carleton Optical, Chesham, UK) for 30 minutes (6 cycles of 5 minutes each).

Trial Locations (1)

1000

Fanka Gilevska, Skopje

All Listed Sponsors
lead

Sistina Ophthalmology Hospital

OTHER

NCT06522789 - Preoperative Corneal Measurements Estimate the Corrected Distance Visual Acuity After Corneal Cross-linking | Biotech Hunter | Biotech Hunter