Comparison Study of EAP and CG Regimens for Mobilizing Hematopoietic Stem Cells in Multiple Myeloma Patients

PHASE3RecruitingINTERVENTIONAL
Enrollment

99

Participants

Timeline

Start Date

August 31, 2024

Primary Completion Date

December 31, 2026

Study Completion Date

December 31, 2026

Conditions
Multiple MyelomaHematopoietic Stem Cell Mobilization
Interventions
DRUG

Etoposide

Day 1\~Day 2: 75mg/m\^2

DRUG

Cytarabine

Day 1\~Day 2: 200g/m\^2, q12h

DRUG

Pegfilgrastim

Day 6: 6mg

DRUG

Cyclophosphamide

Day 1\~Day 2: 1~2g/m\^2

DRUG

G-CSF

Subcutaneous injection at dose 5ug/kg, from day 6 until the end of mobilization.

DRUG

G-CSF

Starting from the 9th day, if the white blood cell count is less than 20,000/μL, administer G-CSF at a dose of 5μg/kg by subcutaneous injection until the collection is completed.

Trial Locations (16)

Unknown

RECRUITING

Dongyang People's Hospital, Dongyang

RECRUITING

The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou

RECRUITING

Tongde Hospital of Zhejiang Province, Hangzhou

RECRUITING

Huzhou central hospital, Huzhou

RECRUITING

The First Hospital of Jiaxing, Jiaxing

RECRUITING

Jinhua Municipal Central Hospital, Jinhua

RECRUITING

Jinhua People's Hospital, Jinhua

RECRUITING

Lishui Central Hospital, Lishui

RECRUITING

Ningbo Medical Center Lihuili Hospital, Ningbo

RECRUITING

The Affiliated People's Hospital of Ningbo University, Ningbo

RECRUITING

Shaoxing People's Hospital, Shaoxing

RECRUITING

Shaoxing Second Hospital, Shaoxing

RECRUITING

Taizhou Central Hospital, Taizhou

RECRUITING

Taizhou Hospital of Zhejiang Province, Taizhou

RECRUITING

The First Affiliated Hospital of Wenzhou Medical University, Wenzhou

RECRUITING

The Second Affiliated Hospital of Wenzhou Medical University, Wenzhou

All Listed Sponsors
collaborator

First Affiliated Hospital of Zhejiang University

OTHER

collaborator

First Affiliated Hospital of Wenzhou Medical University

OTHER

collaborator

Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University

OTHER

collaborator

The Central Hospital of Lishui City

OTHER

collaborator

Jinhua People's Hospital

OTHER

collaborator

Shaoxing People's Hospital

OTHER

collaborator

Shaoxing Second Hospital

OTHER

collaborator

Zhejiang Provincial Tongde Hospital

OTHER

collaborator

Taizhou Hospital

OTHER

collaborator

Dongyang People's Hospital

OTHER

collaborator

Affiliated Hospital of Jiaxing University

OTHER

collaborator

Huizhou Municipal Central Hospital

OTHER

collaborator

Second Affiliated Hospital of Wenzhou Medical University

OTHER

collaborator

Ningbo Medical Center Lihuili Hospital

OTHER_GOV

collaborator

Jinhua Municipal Central Hospital

OTHER

lead

The Affiliated People's Hospital of Ningbo University

OTHER_GOV