Study of Infantile Lower Limb Malformations and Deformities

RecruitingOBSERVATIONAL
Enrollment

1,000

Participants

Timeline

Start Date

October 31, 2024

Primary Completion Date

May 31, 2028

Study Completion Date

May 31, 2029

Conditions
Deformity of Limb
Interventions
OTHER

Conservative treatment

Patients are provided with physiotherapy support and the provision of prostheses with the goal of ensuring as much walking functionality as possible.

PROCEDURE

Single or multi-stage surgery

Correction of the deformity is pursued by one or more surgical procedures with the timing and the techniques (growth modulation, acute correction, gradual correction, soft tissues procedures, combined techniques) chosen according to the surgeon's preference to achieve the maximum possible walking functionality without orthopedic aids.

PROCEDURE

Amputation

Limb surgery, whether or not associated with realignment or soft-tissue surgery, is performed, aimed at providing the maximum possible walking function through a prosthesis.

Trial Locations (7)

40136

RECRUITING

IRCCS Istituto Ortopedico Rizzoli, Bologna

Unknown

NOT_YET_RECRUITING

Istituto Giannina Gaslini, Genova

NOT_YET_RECRUITING

Galeazzi Orthopedic Institute, Milan

NOT_YET_RECRUITING

Policlinico San Matteo, Pavia

NOT_YET_RECRUITING

Istituto Nazionale Tumori Regina Elena, Roma

NOT_YET_RECRUITING

Ospedale Pediatrico Bambino Gesù, Roma

NOT_YET_RECRUITING

Istituto Clinico Humanitas, Rozzano

All Listed Sponsors
collaborator

Ospedale Pediatrico Bambino Gesù

UNKNOWN

collaborator

Istituto Giannina Gaslini

OTHER

collaborator

Galeazzi Orthopedic Institute

UNKNOWN

collaborator

Istituto Nazionale Tumori Regina Elena

UNKNOWN

collaborator

Policlinico San Matteo

UNKNOWN

collaborator

Istituto Clinico Humanitas

OTHER

lead

Istituto Ortopedico Rizzoli

OTHER