A Novel Imaging Modality to Evaluate Radiation-Induced Uterine Injury

NARecruitingINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

February 25, 2025

Primary Completion Date

July 31, 2026

Study Completion Date

March 31, 2027

Conditions
Uterine Injury
Interventions
DIAGNOSTIC_TEST

MRI, SWE, and US evaluation

"We will perform SWE and MRI sampling of the uterus from fundus to lower uterine segment with at least two points each from the upper, mid, and lower thirds of the uterus. SWE and MRI will be performed at time of study recruitment. US procedures will be transabdominal. When possible, we will also collect transvaginal US. MRI images will also be sampled from existing pretreatment studies performed as standard of care. All images will be evaluated for the presence and degree of fibrosis. We will compare SWE and MRI post-treatment. We will also compare pre-and post-treatment MRI.~We will perform US and estimate uterine volumes and arterial resistance. Use descriptive statistics to compare values to age-matched controls"

Trial Locations (1)

80045

RECRUITING

University of Colorado, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER