First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b

PHASE1CompletedINTERVENTIONAL
Enrollment

62

Participants

Timeline

Start Date

December 12, 2017

Primary Completion Date

July 9, 2021

Study Completion Date

July 9, 2021

Conditions
Platinum Resistant Ovarian CancerNon Small Cell Lung Cancer Metastatic
Interventions
DRUG

upifitamab rilsodotin

"XMT-1536 will be administered once every 28 days until disease progression, unacceptable toxicity, or either the patient or study physician determines it is in the best interest of the patient to discontinue participation in the study.~For sites participating in the sub-study, patients with platinum -resistant ovarian cancer will have the option to enroll in this sub-study to evaluate potential changes in the QTc interval following administration of XMT-1536"

Trial Locations (1)

73104

University of Oklahoma, Oklahoma City

Sponsors
All Listed Sponsors
lead

Mersana Therapeutics

INDUSTRY

NCT06517433 - First-in-Human Dose Escalation Study of XMT-1536 in Cancers Likely to Express NaPi2b | Biotech Hunter | Biotech Hunter