NCT06516133View on ClinicalTrials.gov

Online Adaptive Radiotherapy for Nasopharyngeal Carcinoma

PHASE3RecruitingINTERVENTIONAL
Enrollment

494

Participants

Timeline

Start Date

May 17, 2024

Primary Completion Date

December 31, 2030

Study Completion Date

December 31, 2030

Conditions
Nasopharyngeal Carcinoma
Interventions
RADIATION

Intensity modulated radiation therapy (IMRT) with conventional planning target volume (PTV) margin and without online adaptive radiotherapy

"Radiation: Complete the full course of radiotherapy using the original treatment plan.~Planning target volume (PTV) margin: 3mm;"

DRUG

Chemotherapy

Chemotherapy: If given, platinum-based.

RADIATION

Intensity modulated radiation therapy (IMRT) with smaller planning target volume (PTV) margin and online adaptive radiotherapy

"Radiation: During the course of radiotherapy, the treatment plan is adjusted online based on the anatomical and dosimetric changes in the target volumes and organs at risk of patients.~planning target volume (PTV) margin: smaller."

DRUG

Chemotherapy

Chemotherapy: If given, platinum-based

Trial Locations (1)

510060

RECRUITING

Sun Yat-sen University Cancer Center, Guangzhou

All Listed Sponsors
lead

Sun Yat-sen University

OTHER